Patients & Families

Hydrocephalus is a condition that occurs when fluid builds up in the skull and causes the brain to swell. The name means “water on the brain.”

Brain damage can occur as a result of the fluid buildup. This can lead to developmental, physical, and intellectual impairments. It requires treatment to prevent serious complications.¹

Image Source: https://www.healthline.com/health/hydrocephalus

In most cases, a shunt is surgically inserted to drain the excess fluid into the patient’s chest or abdominal cavity. The shunt is a drainage system made of a long tube with a valve. The valve helps CSF flow at a normal rate and in the right direction. Excess fluid drains from the brain and out the other end of the tube, where it can be more easily absorbed. A shunt implant is typically permanent and has to be monitored regularly.¹

An estimated 50% of shunts in the pediatric population fail within two years of placement and repeated neurosurgical operations are often required.

The most common shunt complications are malfunction and infection.

Shunt malfunction is a partial or complete blockage of the shunt that causes it to function intermittently or not at all. When a blockage occurs, CSF accumulates and can result in symptoms of untreated hydrocephalus.

Shunt infection is usually caused by a person’s own bacterial organisms and isn’t acquired from other children or adults who are ill. The most common infection is Staphylococcus Epidermidis, which is normally found on the surface of a person’s skin and in the sweat glands and hair follicles deep within the skin. This type of infection is most likely seen one to three months after surgery, but can occur up to six months after the placement of a shunt.²

The ReFlow™ Ventricular system is a game changer in the current options for treating hydrocephalus. Through personal engagement with hydrocephalus experts, the broader scientific community, and with patients and families just like you, we have developed an alternative shunt system designed to address one of the most common problems in Hydrocephalus: non-flowing shunts.

The ReFlow™ Ventricular System is comprised of a “Flusher” and a specially designed Ventricular Catheter, and can be connected to a standard commercial flow regulator CSF shunt valve and peritoneal catheter.

When there is flow, or the shunt is functioning normally, the Flusher is passive and flow is regulated by the flow regulator valve. When the Ventricular Catheter is occluded, usually due to blocked inlet holes in the ventricular catheter, a press of the Flusher by a qualified clinician sends a small, controlled pulse of fluid toward the Ventricular Catheter in an effort to dislodge any choroid plexus or blockages that are hindering flow through the Ventricular Catheter.

The Reflow™ Ventricular System’s ventricular catheter has an additional, ‘relief membrane’ backup feature. If the Flusher is unable to unblock the standard inlet holes of the Ventricular Catheter, the small controlled pulse of fluid from the flusher has been specifically designed and tested to open the ‘relief membrane’ to make an additional opening in the Ventricular Catheter to re-establish flow.

Instead of having a shunt that would typically be accessed and corrected through an immediate, emergency brain surgery or an invasive intervention (when a malfunction happens such as suspected blocked ventricular catheter); you or your child would be equipped with a shunt system that can be accessed by your physician in a regular medical appointment, for a procedure that offers you the chance to potentially avoid emergency surgery for a better clinical outcome.